Interestingly, RELM-β and Resistin share similar characteristics, such as an additional cysteine residue within the variable N-terminal region, and they are both homodimeric proteins. However, the RELM-β is expressed only in the gastrointestinal track (especially the colon) while in contrast, Resistin secreted exclusively by adipocytes. Currently, the biological function of these proteins, as well as their molecular targets is largely unknown. Recombinant Human RELM-beta produced in E. coli is a disulfide-linked homodimer with a total molecular weight of 19 kDa, made up of two 89 amino acid residue chains.