| 產(chǎn)品名稱 | UNC 9994 hydrochloride |
| 產(chǎn)品貨號(hào) | Axon 2562 CAS [N.A.] MF C21H22Cl2N2OS.HClMW 457.84 Purity: 99% Soluble in DMSO Description Unique, β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in β-arrestin-2 knockout mice. KEYWORDS: UNC 9994 hydrochloride | supplier | D2 agonist | Axon Medchem | Axon 2562 | UNC9994 | CAS [1354030-51-5] | Dopamine | D2 | Agonist | GPCR | D2R | β-arrestin | beta-arrestin | antipsychotic |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
UNC 9994 hydrochlorideAxon 2562 CAS [N.A.] MF C21H22Cl2N2OS.HCl
DescriptionUnique, β-arrestin-biased functionally selective dopamine D2 receptor (D2R) agonist (Ki value 30 nM; EC50 value 50 nM in β-arrestin-2 recruitment assay) that exhibits antipsychotic activity in vivo. UNC9994 markedly inhibited PCP-induced hyperlocomotion in wild-type mice, which effect was completely abolished in β-arrestin-2 knockout mice. KEYWORDS: UNC 9994 hydrochloride | supplier | D2 agonist | Axon Medchem | Axon 2562 | UNC9994 | CAS [1354030-51-5] | Dopamine | D2 | Agonist | GPCR | D2R | β-arrestin | beta-arrestin | antipsychotic
β-Arrestin-biased functionally selective dopamine D2R agonist
Chemical name5-(3-(4-(2,3-dichlorophenyl)piperidin-1-yl)propoxy)benzo[d]thiazole hydrochloride Parent CAS No.[1354030-51-5] |
| 產(chǎn)品資料 |
