產(chǎn)品名稱 Cuspin-1
產(chǎn)品貨號(hào) Axon 2438 CAS [337932-29-3] MF C13H10BrNOMW 276.13 Purity: 99% Soluble in DMSO Description Small molecule upregulator of the Survival of Motor Neuron protein (SMN; EC50 value 18 μM in SMA patient fibroblast cells); a tool compound that revealed that increasing Ras signaling upregulates SMN protein levels by increased phosphorylation of Erk, an important member of the Ras-Raf-MEK signaling cascade. KEYWORDS: Cuspin 1 | Supplier | SMN upregulator | Axon Medchem | Axon 2438 | Cuspin1 | CAS [337932-29-3] | GTP | RAS | RAF | MEK | ERK | Activator | Enzymes | Survival of Motor Neuron Protein | SMN | SMA | fibroblasts | Spliceosome | RNP
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產(chǎn)品品牌 axonmedchem
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Cuspin-1

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2438

CAS [337932-29-3]

MF C13H10BrNO
MW 276.13

  • Purity: 99%
  • Soluble in DMSO

Cuspin-1

Description

Small molecule upregulator of the Survival of Motor Neuron protein (SMN; EC50 value 18 μM in SMA patient fibroblast cells); a tool compound that revealed that increasing Ras signaling upregulates SMN protein levels by increased phosphorylation of Erk, an important member of the Ras-Raf-MEK signaling cascade.

KEYWORDS: Cuspin 1 | Supplier | SMN upregulator | Axon Medchem | Axon 2438 | Cuspin1 | CAS [337932-29-3] | GTP | RAS | RAF | MEK | ERK | Activator | Enzymes | Survival of Motor Neuron Protein | SMN | SMA | fibroblasts | Spliceosome | RNP
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