產(chǎn)品名稱

WH-4-023

產(chǎn)品貨號(hào)

Axon 2381 CAS [837422-57-8] MF C32H36N6O4MW 568.67 Purity: 99% Soluble in DMSO Description Orally active inhibitor of Lck and Src (IC50 values 2 nM and 6 nM for Lck and Src, respectively) with an >300-fold selectivity over p38α and KDR. *Promotion

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產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

WH-4-023

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2381

CAS [837422-57-8]

MF C32H36N6O4
MW 568.67

Purity: 99%
Soluble in DMSO

WH-4-023

Description

Orally active inhibitor of Lck and Src (IC50 values 2 nM and 6 nM for Lck and Src, respectively) with an >300-fold selectivity over p38α and KDR.

*Promotion: WH-4-023 is an important componant of Inhibitor Set(s):

Axon 5011

KEYWORDS: WH-4-023 | supplier | Lck/Src inhibitor | WH4-023 | WH4023 |?CAS [837422-57-8] | Lck | SRC | IL-2 | T-Cell | Antiinflammatory | inflammation | NK-Cell

M.W. Martin et al. Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity. J. Med. Chem. 2006, 49, 4981-4991.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology Immunology Pain & Inflammation Stem Cell SRC Lck EC 2.7.10.2

Orally active src-family selective lck inhibitor

Chemical name

2,6-dimethylphenyl 2,4-dimethoxyphenyl(2-(4-(4-methylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)carbamate

Parent CAS No.

[837422-57-8]

產(chǎn)品資料