| 產(chǎn)品名稱 | SPL-B - Spindlactone B |
| 產(chǎn)品貨號 | Axon 2474 CAS [1465248-60-5] MF C27H22N2O5MW 454.47 Purity: 98% Soluble in 0.1N HCl(aq) and DMSO Description Orally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and suppresses in vivo tumor growth. KEYWORDS: SPL-B | supplier | TACC3 inhibitor | Spindlactone B | SPLB | CAS [1465248-60-5] | microtubules | MTs | TACC | Inhibitor | proteins | mitotic spindle | assembly | mitosis | centrosomal | TOGp | Aurora A | coumarin | cell-cycle regulation | differentiation |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
SPL-B - Spindlactone BAxon 2474 CAS [1465248-60-5] MF C27H22N2O5
DescriptionOrally active inhibitor of transforming acidic coiled-coil protein (TACC3) that selectively inhibits the nucleation of centrosome microtubules in ovarian cancer cells, without affecting spindle assembly in normal cells. SPL significantly inhibits mitosis in cancer cells and suppresses in vivo tumor growth. KEYWORDS: SPL-B | supplier | TACC3 inhibitor | Spindlactone B | SPLB | CAS [1465248-60-5] | microtubules | MTs | TACC | Inhibitor | proteins | mitotic spindle | assembly | mitosis | centrosomal | TOGp | Aurora A | coumarin | cell-cycle regulation | differentiation
Inhibitor of TACC3 that inhibits nucleation of centrosome microtubules
Chemical name8'-((ethyl(pyridin-4-ylmethyl)amino)methyl)-7'-hydroxy-2H,2'H-3,4'-bichromene-2,2'-dione Parent CAS No.[1465248-60-5] |
| 產(chǎn)品資料 |
