產(chǎn)品名稱 TH 1834
產(chǎn)品貨號(hào) Axon 2339 CAS [N.A.] MF C33H40N6O3.2HClMW 641.63 Purity: 99% Soluble in water and DMSO Description Tip60 histone acetyltransferase inhibitor. Treating cells with TH1834 results in apoptosis and increased unrepaired DNA damage (following ionizing radiation treatment) in breast cancer but not control cell lines. Furthermore, TH 1834 did not affect the activity of related HAT MOF, as indicated by H4K16Ac, demonstrating specificity. References Certificates Categories Extra info C. Gao et al. Rational design and validation of a Tip60 histone acetyltransferase inhibitor. Sci. Rep. 2014, 4, 5372. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics HAT Transcription Factors p53-Tumor Suppression Wnt-β-Catenin NF-κB JAK-STAT DNA-damage Response EC 2.3.1.48 Tip60 histone acetyltransferase inhibitor Chemical name 2-(5-(4-((phenethyl(4-(4-(pyrrolidin-1-ylmethyl)phenoxy)butyl)amino)methyl)phenyl)-2H-tetrazol-2-yl)acetic acid dihydrochloride Parent CAS No. [N.A.] Order Size Unit Price Stock 5 mg €135.00 In Stock
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TH 1834

Based on 2435 publications in PubMed 10 10 2435

Axon 2339

CAS [N.A.]

MF C33H40N6O3.2HCl
MW 641.63

  • Purity: 99%
  • Soluble in water and DMSO

TH 1834

Description

Tip60 histone acetyltransferase inhibitor. Treating cells with TH1834 results in apoptosis and increased unrepaired DNA damage (following ionizing radiation treatment) in breast cancer but not control cell lines. Furthermore, TH 1834 did not affect the activity of related HAT MOF, as indicated by H4K16Ac, demonstrating specificity.

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