產(chǎn)品名稱 AZ 20
產(chǎn)品貨號 Axon 2345 CAS [1233339-22-4] MF C21H24N4O3SMW 412.51 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent, orally active and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity (IC50 value 5 nM). AZ 20 potently inhibits the growth of LoVo colorectal adenocarcinoma tumor cells in vitro, and is a useful compound to explore ATR pharmacology in vivo. KEYWORDS:?AZ 20 | supplier | ATR inhibitor | AZ20 | AZ-20 | CAS [1233339-22-4] | DNA-damage response | ATR | ATM | DNA | damage control | cancer | oncology | Checkpoint | cell cycle control
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產(chǎn)品品牌 axonmedchem
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AZ 20

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2345

CAS [1233339-22-4]

MF C21H24N4O3S
MW 412.51

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in 0.1N HCl(aq) and DMSO

AZ 20

Description

Potent, orally active and selective inhibitor of ATR protein kinase with monotherapy in vivo antitumor activity (IC50 value 5 nM). AZ 20 potently inhibits the growth of LoVo colorectal adenocarcinoma tumor cells in vitro, and is a useful compound to explore ATR pharmacology in vivo.

KEYWORDS:?AZ 20 | supplier | ATR inhibitor | AZ20 | AZ-20 | CAS [1233339-22-4] | DNA-damage response | ATR | ATM | DNA | damage control | cancer | oncology | Checkpoint | cell cycle control
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