產(chǎn)品名稱 TAS-103 dihydrochloride - BMS 247615 dihydrochloride
產(chǎn)品貨號(hào) Axon 2914 CAS [174634-09-4] MF C20H19N3O2.2HClMW 406.31 Purity: 99% Soluble in water and DMSO Description TAS-103 dihydrochloride is an anticancer agent targeting topoisomerases I and II with IC50 values of 2 μM and 6.5 μM, respectively. Moreover, TAS-103 dihydrochloride has a strong cytotoxic effect on P388 and KB cells with IC50 values of 0.0011 μM and 0.0096 μM, respectively. Also, TAS-103 has strong inhibitory effects on the growth of various mouse and human solid tumors in vivo, as well as high antitumor activity against lung metastatic cancer. KEYWORDS: TAS-103 dihydrochloride | supplier | Topo 1/2 inhibitor | BMS 247615 dihydrochloride | TAS-103 | TAS103 | BMS247615 | BMS-247615 | CAS [174634-08-3] | CAS [174634-09-4] | DNA-RNA | TOPO | Inhibitor | Enzymes | Topoisomerase | Lung cancer
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TAS-103 dihydrochloride - BMS 247615 dihydrochloride

Based on 39 reference(s) in Google Scholar 8 10 39

Axon 2914

CAS [174634-09-4]

MF C20H19N3O2.2HCl
MW 406.31

  • Purity: 99%
  • Soluble in water and DMSO

TAS-103 dihydrochloride

Description

TAS-103 dihydrochloride is an anticancer agent targeting topoisomerases I and II with IC50 values of 2 μM and 6.5 μM, respectively. Moreover, TAS-103 dihydrochloride has a strong cytotoxic effect on P388 and KB cells with IC50 values of 0.0011 μM and 0.0096 μM, respectively. Also, TAS-103 has strong inhibitory effects on the growth of various mouse and human solid tumors in vivo, as well as high antitumor activity against lung metastatic cancer.

KEYWORDS: TAS-103 dihydrochloride | supplier | Topo 1/2 inhibitor | BMS 247615 dihydrochloride | TAS-103 | TAS103 | BMS247615 | BMS-247615 | CAS [174634-08-3] | CAS [174634-09-4] | DNA-RNA | TOPO | Inhibitor | Enzymes | Topoisomerase | Lung cancer

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