產(chǎn)品名稱 SCR7 pyrazine
產(chǎn)品貨號 Axon 2531 CAS [14892-97-8] MF C18H12N4OSMW 332.38 Purity: 99% Soluble in DMSO Description DNA ligase IV mediated inhibitor of NHEJ (non-homologous end joining) that increases the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells up to 19-fold. Note
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產(chǎn)品品牌 axonmedchem
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SCR7 pyrazine

Based on 31 publications in PubMed 9 10 31

Axon 2531

CAS [14892-97-8]

MF C18H12N4OS
MW 332.38

  • Purity: 99%
  • Soluble in DMSO

SCR7 pyrazine

Description

DNA ligase IV mediated inhibitor of NHEJ (non-homologous end joining) that increases the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells up to 19-fold.

Note: Axon Medchem confirmed that the active chemical entity of SCR7, as described by Srivastava and others, is actually SCR7 pyrazine (Axon 2531). Careful application of the synthetic conditions described in this paper and comparison with authentic SCR7 pyrazine reveals identical chemical products.

KEYWORDS: SCR7 pyrazine | supplier | NHEJ/DNA ligase IV inhibitor | CAS [14892-97-8] | [67648-82-2] | [1538566-74-3]?| DNA-RNA | DNA ligase | Inhibitor | Non-homologous end joining | CRISPR | Cas9 | DSB | double strand breaks | DNA repair | tumor progression
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