產(chǎn)品名稱

AZD 6482 - KIN-193

產(chǎn)品貨號(hào)

Axon 2926 CAS [1173900-33-8] MF C22H24N4O4MW 408.45 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description AZD 6482 is a potent and selective inhibitor of the p110β isoform of PI3K with an IC50 value of 0.69 nM. In addition, AZD 6482 can inhibit the growth of tumors driven by p110β or PTEN-loss in vivo. KEYWORDS: AZD 6482 | supplier | PI3K p110β inhibitor | KIN-193 | AZD6482 | AZD-6482 | KIN193 | KIN 193 | CAS [1173900-33-8] | Phosphatidylinositol | PI3K | Inhibitor | Enzymes | PTEN

產(chǎn)品價(jià)格

現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

AZD 6482 - KIN-193

Based on 21 reference(s) in Google Scholar 8 10 21

Axon 2926

CAS [1173900-33-8]

MF C22H24N4O4
MW 408.45

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

AZD 6482

Description

AZD 6482 is a potent and selective inhibitor of the p110β isoform of PI3K with an IC50 value of 0.69 nM. In addition, AZD 6482 can inhibit the growth of tumors driven by p110β or PTEN-loss in vivo.

KEYWORDS: AZD 6482 | supplier | PI3K p110β inhibitor | KIN-193 | AZD6482 | AZD-6482 | KIN193 | KIN 193 | CAS [1173900-33-8] | Phosphatidylinositol | PI3K | Inhibitor | Enzymes | PTEN

J Ni et al. Functional characterization of an isoform-selective inhibitor of PI3K-p110? as a potential anticancer agent. Cancer Discov. 2012 May;2(5):425-33.

Certificate of Analysis
Material Safety Data Sheet

Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153

PI3K inhibitor (p110 β specific)

Chemical name

(R)-2-(1-(7-Methyl-2-morpholino-4-oxo-4H-pyrido[1,2-a]pyrimidin-9-yl)ethylamino)benzoic acid

Parent CAS No.

[1173900-33-8]

產(chǎn)品資料