產(chǎn)品名稱 LX2343
產(chǎn)品貨號(hào) Axon 2869 CAS [333745-53-2] MF C22H19ClN2O6SMW 474.91 Purity: 99% Soluble in DMSO Description Inhibitor of human β-secretase (BACE-1) and PI3K (non-ATP competitive) with IC50 values of 11 μM and 16 μM, respectively. Moreover, LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion. Potentially effective in the treatment of Alzheimer's disease. KEYWORDS: LX2343 | supplier | BACE inhibitor | LX 2343 | LX-2343 | CAS [333745-53-2] | Amyloids | BACE-1 | Amyloid-β | PI3K | Inhibitor | Enzymes | Alzheimer's disease | Cognitive Dysfunction
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LX2343

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2869

CAS [333745-53-2]

MF C22H19ClN2O6S
MW 474.91

  • Purity: 99%
  • Soluble in DMSO

LX2343

Description

Inhibitor of human β-secretase (BACE-1) and PI3K (non-ATP competitive) with IC50 values of 11 μM and 16 μM, respectively. Moreover, LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion. Potentially effective in the treatment of Alzheimer's disease.

KEYWORDS: LX2343 | supplier | BACE inhibitor | LX 2343 | LX-2343 | CAS [333745-53-2] | Amyloids | BACE-1 | Amyloid-β | PI3K | Inhibitor | Enzymes | Alzheimer's disease | Cognitive Dysfunction

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