| 產(chǎn)品名稱 | 3PO |
| 產(chǎn)品貨號(hào) | Axon 2175 CAS [18550-98-6] MF C13H10N2OMW 210.23 Purity: 99% Soluble in DMSO Description Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. Potential application as suppressor of tumor glucose metabolism and growth of non-small cell lung cancer cells. The PFKFB3 family member has the highest kinase:bisphosphatase ratio (740:1) of the four known PFKFB family members. 3PO markedly attenuated the stimulation of F2,6BP synthesis, 2-[1-14C]-deoxy-D-glucose uptake, lactate secretion, TNF-α secretion and T cell aggregation and proliferation. KEYWORDS: 3PO | supplier | PFKFB3 inhibitor | 3PO | 3PO | CAS [18550-98-6] | Fructose 6-phosphate | PFKFB3 | F6P | F2 | 6BP | Inhibitor | Enzymes |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
3POAxon 2175 CAS [18550-98-6] MF C13H10N2O
DescriptionInhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis. Potential application as suppressor of tumor glucose metabolism and growth of non-small cell lung cancer cells. The PFKFB3 family member has the highest kinase:bisphosphatase ratio (740:1) of the four known PFKFB family members. 3PO markedly attenuated the stimulation of F2,6BP synthesis, 2-[1-14C]-deoxy-D-glucose uptake, lactate secretion, TNF-α secretion and T cell aggregation and proliferation. KEYWORDS: 3PO | supplier | PFKFB3 inhibitor | 3PO | 3PO | CAS [18550-98-6] | Fructose 6-phosphate | PFKFB3 | F6P | F2 | 6BP | Inhibitor | Enzymes
Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis.
Chemical name(E)-3-(pyridin-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one Parent CAS No.[18550-98-6] |
| 產(chǎn)品資料 |
