產(chǎn)品名稱 NU 1025
產(chǎn)品貨號 Axon 1370 CAS [90417-38-2] MF C9H8N2O2MW 176.17 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Potent inhibitor of poly(ADP-ribose) polymerase (PARP); reported to have neuroprotective effects References Certificates Categories Extra info R Kaundal et al.?Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation.?Life Sciences 2006, 79(24), 2293-302. ? KJ Bowman et al. Potentiation of anti-cancer agent cytotoxicity by the potent poly(ADP-ribose) polymerase inhibitors NU1025 and NU1064. Br. J. Cancer. 1998,?78?1269. ? CA Delaney et al. Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines. Clin. Cancer Res. 2000, 6, 2860. Certificate of Analysis Material Safety Data Sheet Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 2.4.2.30 PARP PARP inhibitor Chemical name 8-Hydroxy-2-methyl-3H-quinazolin-4-one Parent CAS No. [90417-38-2] Order Size Unit Price Stock 10 mg €80.00 In Stock
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