產(chǎn)品名稱 A 922500
產(chǎn)品貨號 Axon 2059 CAS [959122-11-3] MF C26H24N2O4MW 428.48 Purity: 98% Optical purity: 97% d.e. Soluble in DMSO Description Highly potent and selective diacylglycerol acyltransferase (DGAT) isomer 1 (DGAT-1) inhibitor with nanomolar potency References Certificates Categories Extra info G Zhao et al. Validation of diacyl glycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor. J. Med. Chem. 2008, 51(3), 380-383.? ? AJ King et al. Diacylglycerol Acyltransferase 1 Inhibition Lowers Serum Triglycerides in the Zucker Fatty Rat and the Hyperlipidemic Hamster. J. Pharmacol. Exp. Ther.?2009, 330(2), 526-531.? ? AJ King et al. In vivo efficacy of acyl CoA: diacylglycerol acyltransferase (DGAT) 1 inhibition in rodent models of postprandial hyperlipidemia. Eur. J. Pharmacol. 2010, 637(1-3), 155-161.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Diabetes & Metabolism DGAT-1 EC 2.3.1.20 Highly potent and selective diacylglycerol acyltransferase 1 (DGAT-1) inhibitor Chemical name (1R,2R)-2-(4'-(3-phenylureido)biphenylcarbonyl)cyclopentanecarboxylic acid Parent CAS No. [959122-11-3] Order Size Unit Price Stock 5 mg €105.00 In Stock
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A 922500

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2059

CAS [959122-11-3]

MF C26H24N2O4
MW 428.48

  • Purity: 98%
  • Optical purity: 97% d.e.
  • Soluble in DMSO

A 922500

Description

Highly potent and selective diacylglycerol acyltransferase (DGAT) isomer 1 (DGAT-1) inhibitor with nanomolar potency
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