產(chǎn)品名稱 JK184
產(chǎn)品貨號 Axon 2654 CAS [315703-52-7] MF C19H18N4OSMW 350.44 Purity: 100% Soluble in DMSO and Ethanol Description Antagonist of Hedgehog (Hh) signaling (IC50 value of 30 nM for inhibition of Gli-dependent transcriptional activity) and a potent inhibitor of microtubule assembly that exhibits good antiproliferative activity both in vitro and in vivo. JK184 appears to act by inhibition of Adh7 (Kd value 210 nM in a assay for enzymatic oxidation of retinol). KEYWORDS:?JK184 | supplier | Hedgehog inhibitor | JK-184 | CAS [315703-52-7] | [466638-53-9] | Hedgehog | ADH | Antagonist | Hh | Smoothened | Smo | Patched | Ptch1 | Ptc | Gli | microtubules | Sonic | shh | Indian | ihh | Desert | dhh
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產(chǎn)品品牌 axonmedchem
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JK184

Based on 14 reference(s) in Google Scholar 10 10 14

Axon 2654

CAS [315703-52-7]

MF C19H18N4OS
MW 350.44

  • Purity: 100%
  • Soluble in DMSO and Ethanol

JK184

Description

Antagonist of Hedgehog (Hh) signaling (IC50 value of 30 nM for inhibition of Gli-dependent transcriptional activity) and a potent inhibitor of microtubule assembly that exhibits good antiproliferative activity both in vitro and in vivo. JK184 appears to act by inhibition of Adh7 (Kd value 210 nM in a assay for enzymatic oxidation of retinol).

KEYWORDS:?JK184 | supplier | Hedgehog inhibitor | JK-184 | CAS [315703-52-7] | [466638-53-9] | Hedgehog | ADH | Antagonist | Hh | Smoothened | Smo | Patched | Ptch1 | Ptc | Gli | microtubules | Sonic | shh | Indian | ihh | Desert | dhh
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