| 產(chǎn)品名稱 | R 428 dihydrochloride - BGB324 | Bemcentinib |
| 產(chǎn)品貨號(hào) | Axon 1946 CAS [N.A.] MF C30H34N8.2HClMW 579.57 Purity: 99% Optical purity: 99% ee Soluble in water and DMSO Description Potent and selective inhibitor of Axl receptor tyrosine kinases (IC50: 14 nM); R428 inhibits Axl kinase and blocks Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Note: The hydrochloride salt of R428 is water-soluble and has an improved solubility in DMSO in comparison with its free base KEYWORDS:?R 428 dihydrochloride | supplier | Axl inhibitor | BGB324 | R428 HCl | R-428 | BGB-324 | CAS [1037624-75-1] | Gas6 | Axl | receptor tyrosine kinase | RTK | Akt | breast cancer | proinflammatory | cytokine production |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
R 428 dihydrochloride - BGB324 | BemcentinibAxon 1946 CAS [N.A.] MF C30H34N8.2HCl
DescriptionPotent and selective inhibitor of Axl receptor tyrosine kinases (IC50: 14 nM); R428 inhibits Axl kinase and blocks Axl-dependent events, including Akt phosphorylation, breast cancer cell invasion, and proinflammatory cytokine production. Note: The hydrochloride salt of R428 is water-soluble and has an improved solubility in DMSO in comparison with its free base KEYWORDS:?R 428 dihydrochloride | supplier | Axl inhibitor | BGB324 | R428 HCl | R-428 | BGB-324 | CAS [1037624-75-1] | Gas6 | Axl | receptor tyrosine kinase | RTK | Akt | breast cancer | proinflammatory | cytokine production
Selective inhibitor of Axl receptor tyrosine kinases
Chemical name1H-1,2,4-Triazole-3,5-diamine, 1-(6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-c]pyridazine-3-yl)-N3-[(7S)-6,7,8,9-tetrahydro-7-(1-pyrrolidinyl)-5H-benzocyclohepten-2-yl]- dihydrochloride Parent CAS No.[1037624-75-1] |
| 產(chǎn)品資料 |
