產(chǎn)品名稱

Apilimod - STA 5326

產(chǎn)品貨號

Axon 1369 CAS [541550-19-0] MF C23H26N6O2MW 418.49 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.The water-soluble dimesylate salt is available as well (Axon 2500).? Note:

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現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Apilimod - STA 5326

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1369

CAS [541550-19-0]

MF C23H26N6O2
MW 418.49

Purity: 99%
Soluble in 0.1N HCl(aq) and DMSO

Apilimod

Description

Potent and orally active inhibitor of the cytokines interleukin-12 (IL-12), and interleukin-23 (IL-23) production; potential regulators of certain autoimmune and inflammatory diseases.
The water-soluble dimesylate salt is available as well (Axon 2500).?

Note:?This item is currently suspended due to the request of the developer. You might request a quotation for contract research synthesis. Please contact?us?for conditions and more detailed information.

Wada et al: Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor. Blood, 2007, 109(3), 1156-1164.

Wada et al: IL-12/IL-23 inhibitors: a promising approach to the treatment of inflammatory disorders. Drugs Fut. 2008, 33(1), 49-63.

Certificate of Analysis
Material Safety Data Sheet

Angiogenesis Cell Signaling & Oncology Immunology Pain & Inflammation IL-12 IL-23 Type I

Cytokine inhibitor; IL-12 and IL-23 inhibitor

Chemical name

N-[6-Morpholin-4-yl-2-(2-pyridin-2-yl-ethoxy)-pyrimidin-4-yl]-N'-[1-m-tolyl-meth-(E)-ylidene]-hydrazine

Parent CAS No.

[541550-19-0]

產(chǎn)品資料