| 產(chǎn)品名稱 | NVP-BGJ398 phosphate - BGJ 398 phosphate | Infigratinib phosphate |
| 產(chǎn)品貨號(hào) | Axon 1944 CAS [1310746-10-1] MF C26H34Cl2N7O7PMW 658.47 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Phosphate salt of Axon 1775 KEYWORDS:?NVP-BGJ398 phosphate | supplier | FGFR inhibitor | BGJ 398 phosphate | Infigratinib phosphate | NVPBGJ398 | NVP-BGJ 398 | CAS [1310746-10-1] | [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
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| 產(chǎn)品詳情 |
NVP-BGJ398 phosphate - BGJ 398 phosphate | Infigratinib phosphateAxon 1944 CAS [1310746-10-1] MF C26H34Cl2N7O7P
DescriptionPotent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. Phosphate salt of Axon 1775 KEYWORDS:?NVP-BGJ398 phosphate | supplier | FGFR inhibitor | BGJ 398 phosphate | Infigratinib phosphate | NVPBGJ398 | NVP-BGJ 398 | CAS [1310746-10-1] | [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft
Inhibitor of FGFR tyrosine kinases 1, 2 ,3 and 4
Chemical name3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)-1-methylurea phosphate Parent CAS No.[872511-34-7] |
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