| 產(chǎn)品名稱 | NVP-BGJ398 - BGJ 398 | Infigratinib |
| 產(chǎn)品貨號 | Axon 1775 CAS [872511-34-7] MF C26H31Cl2N7O3MW 560.48 Purity: 99% Soluble in DMSO Description Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3.The phosphate salt of NVP-BGJ398 (Axon 1944) is available as well.? KEYWORDS:?NVP-BGJ398 | supplier | FGFR inhibitor | BGJ 398 | Infigratinib | NVP-BGJ398 | BGJ398 | CAS [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
NVP-BGJ398 - BGJ 398 | InfigratinibAxon 1775 CAS [872511-34-7] MF C26H31Cl2N7O3
DescriptionPotent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively); it showed siginificant antitumor activity in RT112 bladder cancer xenografts models overexpressing wild-type FGFR3. KEYWORDS:?NVP-BGJ398 | supplier | FGFR inhibitor | BGJ 398 | Infigratinib | NVP-BGJ398 | BGJ398 | CAS [872511-34-7] | FGF | RTK | fibroblast growth factor | tyrosine kinases | FGFR1 | FGFR2 | FGFR3 | FGFR4 | antitumor activity | RT112 xenograft
Inhibitor of FGFR tyrosine kinases 1, 2 ,3 and 4
Chemical name3-(2,6-dichloro-3,5-dimethoxyphenyl)-1-(6-(4-(4-ethylpiperazin-1-yl)phenylamino)pyrimidin-4-yl)-1-methylurea Parent CAS No.[872511-34-7] |
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