產(chǎn)品名稱 UF 010
產(chǎn)品貨號 Axon 2518 CAS [537672-41-6] MF C11H15BrN2OMW 271.15 Purity: 98% Soluble in DMSO and Ethanol Description Class I selective HDAC inhibitor (IC50 values 0.5 μM, 0.1 μM, 0.06 μM, and 1.5 μM for HDAC1, HDAC2, HDAC3, and HDAC8 respectively) that inhibits cancer cell proliferation. Consistently induced the accumulation of acetylated histones (H2B, H3, and H4 but no effect on H2A) and p53 in vitro, without affecting α-tubulin. KEYWORDS: UF 010 | supplier | HDAC inhibitor | UF010 | CAS [537672-41-6] | Histone | deacetylase | HDAC | Inhibitor | HDAC1 | HDAC2 | HDAC3 | HDAC8 | tubulin | epigenetic | inflammation | tumor suppressor | antiproliferative
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產(chǎn)品品牌 axonmedchem
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UF 010

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2518

CAS [537672-41-6]

MF C11H15BrN2O
MW 271.15

  • Purity: 98%
  • Soluble in DMSO and Ethanol

UF 010

Description

Class I selective HDAC inhibitor (IC50 values 0.5 μM, 0.1 μM, 0.06 μM, and 1.5 μM for HDAC1, HDAC2, HDAC3, and HDAC8 respectively) that inhibits cancer cell proliferation. Consistently induced the accumulation of acetylated histones (H2B, H3, and H4 but no effect on H2A) and p53 in vitro, without affecting α-tubulin.

KEYWORDS: UF 010 | supplier | HDAC inhibitor | UF010 | CAS [537672-41-6] | Histone | deacetylase | HDAC | Inhibitor | HDAC1 | HDAC2 | HDAC3 | HDAC8 | tubulin | epigenetic | inflammation | tumor suppressor | antiproliferative
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