產(chǎn)品名稱

Tubastatin A hydrochloride

產(chǎn)品貨號(hào)

Axon 2004 CAS [1310693-92-5] MF C20H21N3O2.HClMW 371.86 Purity: 99% Soluble in DMSO Description Tubastatin A is a potent and selective HDAC6 inhibitor (IC50 value of 0.015 μM), which did not display neuronal toxicity, thus forecasting the potential application of this agent to neurodegenerative conditions. Keywords: Tubastatin A hydrochloride | supplier | HDAC6 Inhibitor | CAS [1310693-92-5] | [1252003-15-8] | Histone | HDAC | Inhibitor | Enzymes | Neuroprotective

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產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Tubastatin A hydrochloride

Based on 111 reference(s) in Google Scholar 8 10 111

Axon 2004

CAS [1310693-92-5]

MF C20H21N3O2.HCl
MW 371.86

Purity: 99%
Soluble in DMSO

Tubastatin A hydrochloride

Description

Tubastatin A is a potent and selective HDAC6 inhibitor (IC50 value of 0.015 μM), which did not display neuronal toxicity, thus forecasting the potential application of this agent to neurodegenerative conditions.

KV Butler et al. Rational design and simple chemistry yield a superior, neuroprotective HDAC6 inhibitor, tubastatin A. J Am Chem Soc. 2010 Aug 11;132(31):10842-6.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC

Potent and selective HDAC6 inhibitor

Chemical name

N-Hydroxy-4-((2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)methyl)benzamide hydrochloride

Parent CAS No.

[1252003-15-8]

產(chǎn)品資料