| 產(chǎn)品名稱 | PCI 34051 |
| 產(chǎn)品貨號 | Axon 1853 CAS [950762-95-5] MF C17H16N2O3MW 296.32 Purity: 98% Soluble in DMSO Description Specific and potent histone deacetylase 8 (HDAC8) inhibitor, with >200-fold selectivity over the other HDAC isoforms. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias, but not in other hematopoietic or solid tumor lines References Certificates Categories Extra info S Balasubramanian et al. A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas. Leukemia 2008, 22, 1026-1034.? ? SM Horwitz. The emerging role of histone deacetylase inhibitors in treating T-cell lymphomas. Curr. Hematol. Malig. Rep. 2011, 6(1), 67-72.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics DNA-damage Response EC 3.5.1.98 HDAC HDAC8 Inhibitor Chemical name N-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide Parent CAS No. [950762-95-5] Order Size Unit Price Stock 10 mg €90.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
PCI 34051Axon 1853 CAS [950762-95-5] MF C17H16N2O3
Description
Specific and potent histone deacetylase 8 (HDAC8) inhibitor, with >200-fold selectivity over the other HDAC isoforms. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias, but not in other hematopoietic or solid tumor lines
HDAC8 Inhibitor
Chemical nameN-hydroxy-1-(4-methoxybenzyl)-1H-indole-6-carboxamide Parent CAS No.[950762-95-5] |
| 產(chǎn)品資料 |
