產(chǎn)品名稱

Irestatin 9389

產(chǎn)品貨號

Axon 1656 CAS [626221-47-4] MF C16H13F3N4OS2MW 398.43 Purity: 99% Soluble in DMSO Description A potent inhibitor of the endonuclease IRE1 (IC50 = 6.3 nM) and unfolded protein response (UPR) References Certificates Categories Extra info D Feldman and AC Koong. Irestatin, a potent inhibitor of IRE1α and the unfolded protein response, is a hypoxia-selective cytotoxin and impairs tumor growth. J. Clin. Oncol. (2007 ASCO Ann. Meeting Proc. PI) 2007, 25 (18S), 3514. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Signaling & Oncology EC 2.7.11.1 IRE Endonuclease IRE1 inhibitor; UPR inhibitor Chemical name 2-(3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylthio)-N-(4-methylthiazol-2-yl)acetamide Parent CAS No. [626221-47-4] Order Size Unit Price Stock 10 mg €125.00 In Stock

產(chǎn)品價格

現(xiàn)貨詢價，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Irestatin 9389

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1656

CAS [626221-47-4]

MF C16H13F3N4OS2
MW 398.43

Purity: 99%
Soluble in DMSO

Irestatin 9389

Description

A potent inhibitor of the endonuclease IRE1 (IC50 = 6.3 nM) and unfolded protein response (UPR)

D Feldman and AC Koong. Irestatin, a potent inhibitor of IRE1α and the unfolded protein response, is a hypoxia-selective cytotoxin and impairs tumor growth. J. Clin. Oncol. (2007 ASCO Ann. Meeting Proc. PI) 2007, 25 (18S), 3514.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Signaling & Oncology EC 2.7.11.1 IRE Endonuclease

IRE1 inhibitor; UPR inhibitor

Chemical name

2-(3-cyano-4-(trifluoromethyl)-6,7-dihydro-5H-cyclopenta[b]pyridin-2-ylthio)-N-(4-methylthiazol-2-yl)acetamide

Parent CAS No.

[626221-47-4]

產(chǎn)品資料