產(chǎn)品名稱

Hydroxypioglitazone - M-IV

產(chǎn)品貨號(hào)

Axon 2533 CAS [146062-46-6] MF C19H20N2O4S.HClMW 408.90 Purity: 100% Soluble in DMSO Description Active metabolite of Pioglitazone (M-IV), a PPARγ agonist used for the treatment of diabetes mellitus type 2. Showed modest antihyperglycemic activity compared to Pioglitazone. Moreover, Hydroxypioglitazone is more efficient than Pioglitazone in stimulating lipid synthesis at a 3 μM dose in a 3T3-L1 cell assay. KEYWORDS : Hydroxypioglitazone | supplier | PPARγ agonist | M-IV | CAS [146062-46-6] | [146062-44-4] | Prostaglandins | PPAR | Agonist | diabetes mellitus | type 2 | antihyperglycemic | Pioglitazone | metabolite

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產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

Hydroxypioglitazone - M-IV

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 2533

CAS [146062-46-6]

MF C19H20N2O4S.HCl
MW 408.90

Purity: 100%
Soluble in DMSO

Hydroxypioglitazone

Description

Active metabolite of Pioglitazone (M-IV), a PPARγ agonist used for the treatment of diabetes mellitus type 2. Showed modest antihyperglycemic activity compared to Pioglitazone. Moreover, Hydroxypioglitazone is more efficient than Pioglitazone in stimulating lipid synthesis at a 3 μM dose in a 3T3-L1 cell assay.

S.P. Tanis et al. Synthesis and biological activity of metabolites of the antidiabetic, antihyperglycemic agent pioglitazone. J Med Chem. 1996 Dec 20;39(26):5053-63.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Diabetes & Metabolism Pain & Inflammation NF-κB PPAR NR1C

Active metabolite of Pioglitazone (M-IV), a PPARγ agonist

Chemical name

5-(4-(2-(5-(1-hydroxyethyl)pyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione hydrochloride

Parent CAS No.

[146062-44-4]

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