產(chǎn)品名稱 TCN-201
產(chǎn)品貨號 Axon 2708 CAS [852918-02-6] MF C21H17ClFN3O4SMW 461.89 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors (pIC50 values of 6.8 and 4.3, respectively). The degree of inhibition produced by TCN 201 is dependent on the concentration of the GluN1-site co-agonist, glycine (or D-serine), and is independent of the glutamate concentration. TCN-201 is a negative allosteric modulator of glycine binding. KEYWORDS: TCN-201 | supplier | NR2A antagonist | TCN201 | TCN 201 | CAS [852918-02-6] | Axon Medchem | Axon 2708 | Glutamate | NMDA | Antagonist | Ion Channels
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產(chǎn)品品牌 axonmedchem
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TCN-201

Based on 16 reference(s) in Google Scholar 8 10 16

Axon 2708

CAS [852918-02-6]

MF C21H17ClFN3O4S
MW 461.89

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq) and DMSO

TCN-201

Description

NMDA receptor antagonist selective for NR2A- over NR2B-containing receptors (pIC50 values of 6.8 and 4.3, respectively). The degree of inhibition produced by TCN 201 is dependent on the concentration of the GluN1-site co-agonist, glycine (or D-serine), and is independent of the glutamate concentration. TCN-201 is a negative allosteric modulator of glycine binding.

KEYWORDS: TCN-201 | supplier | NR2A antagonist | TCN201 | TCN 201 | CAS [852918-02-6] | Axon Medchem | Axon 2708 | Glutamate | NMDA | Antagonist | Ion Channels
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