產品名稱 VU 0364770
產品貨號 Axon 1845 CAS [61350-00-3] MF C12H9ClN2OMW 232.67 Purity: 99% Soluble in DMSO Description A systemically active positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4) (EC50: 290 nM); showed efficacy alone or when administered in combination with L-DOPA or an adenosine 2A (A2A) receptor antagonist, in several rodent PD models References Certificates Categories Extra info CK Jones et al. The metabotropic glutamate receptor 4-positive allosteric modulator VU0364770 produces efficacy alone and in combination with L-DOPA or an adenosine 2A antagonist in preclinical (...).?J. Pharmacol. Exp. Ther. 2012, 340(2), 404-21.? Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation mGluR4 C3 Positive allosteric modulator (PAM) of mGluR4 Chemical name N-(4-chlorophenyl)picolinamide Parent CAS No. [61350-00-3] Order Size Unit Price Stock 10 mg €80.00 In Stock
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VU 0364770

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1845

CAS [61350-00-3]

MF C12H9ClN2O
MW 232.67

  • Purity: 99%
  • Soluble in DMSO

VU 0364770

Description

A systemically active positive allosteric modulator (PAM) of metabotropic glutamate receptor subtype 4 (mGluR4) (EC50: 290 nM); showed efficacy alone or when administered in combination with L-DOPA or an adenosine 2A (A2A) receptor antagonist, in several rodent PD models
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