| 產(chǎn)品名稱 | A 784168 |
| 產(chǎn)品貨號(hào) | Axon 1816 CAS [824982-41-4] MF C19H15F6N3O3SMW 479.40 Purity: 98% Soluble in DMSO Description Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50: 24 nM); displayed potent anti-nociceptive effects in a broad range of animal pain models upon oral dosing. This analgesic activity results from its ability to penetrate the central nervous system References Certificates Categories Extra info M Cui et al. TRPV1 receptors in the CNS play a key role in broad-spectrum analgesia of TRPV1 antagonists. J. Neurosci. 2006, 26(37), 9385-9393.? ? SB Brown et al. Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists. Bioorg. Med. Chem. 2008,?16, 8516–8525.? Certificate of Analysis Material Safety Data Sheet CNS Pain & Inflammation TRPV1 Unclassified TRPV1 receptor antagonist Chemical name 1-(3-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethylsulfonyl)phenyl)-1,2,3,6-tetrahydropyridine-4-carboxamide Parent CAS No. [824982-41-4] Order Size Unit Price Stock 5 mg €95.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
A 784168Axon 1816 CAS [824982-41-4] MF C19H15F6N3O3S
Description
Potent and selective antagonist of transient receptor potential vanilloid 1 (TRPV1) receptors (IC50: 24 nM); displayed potent anti-nociceptive effects in a broad range of animal pain models upon oral dosing. This analgesic activity results from its ability to penetrate the central nervous system
TRPV1 receptor antagonist
Chemical name1-(3-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethylsulfonyl)phenyl)-1,2,3,6-tetrahydropyridine-4-carboxamide Parent CAS No.[824982-41-4] |
| 產(chǎn)品資料 |
