產(chǎn)品名稱 FG-2216 - YM 311
產(chǎn)品貨號(hào) Axon 2570 CAS [223387-75-5] MF C12H9ClN2O4MW 280.66 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Orally active HIF prolyl 4-hydroxylase inhibitor (P4-HI; IC50 value 3.9 μM for PHD2) that increases plasma EPO levels up to 30-fold in hemodialysis (HD) patients, and reduces cardiac remodeling after myocardial infarction in rats independent of a reduction of collagen maturation or altering growth factors. KEYWORDS: FG-2216 | supplier | PHD inhibitor | YM 311 | FG2216 | YM311 | CAS [223387-75-5] | Hypoxia-signaling cascade | PHD-2 (HIF1) | PHD-4 (HIF1) | Inhibitor | hypoxia inducible factor | prolyl hydroxylase | EPO | hemodialysis | cardiac remodeling | myocardial infarction | collagen
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FG-2216 - YM 311

Based on 303 reference(s) in Google Scholar 10 10 303

Axon 2570

CAS [223387-75-5]

MF C12H9ClN2O4
MW 280.66

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

FG-2216

Description

Orally active HIF prolyl 4-hydroxylase inhibitor (P4-HI; IC50 value 3.9 μM for PHD2) that increases plasma EPO levels up to 30-fold in hemodialysis (HD) patients, and reduces cardiac remodeling after myocardial infarction in rats independent of a reduction of collagen maturation or altering growth factors.

KEYWORDS: FG-2216 | supplier | PHD inhibitor | YM 311 | FG2216 | YM311 | CAS [223387-75-5] | Hypoxia-signaling cascade | PHD-2 (HIF1) | PHD-4 (HIF1) | Inhibitor | hypoxia inducible factor | prolyl hydroxylase | EPO | hemodialysis | cardiac remodeling | myocardial infarction | collagen
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