產(chǎn)品名稱 Brassinin
產(chǎn)品貨號 Axon 2489 CAS [105748-59-2] MF C11H12N2S2MW 236.36 Purity: 98% Soluble in DMSO Description Bioavailable dithiocarbamate with affinity for indoleamine 2,3-dioxygenase (IDO; Ki value 28 μM for human IDO) showing antifungal and anticancer activity. Moreover, Brassinin suppressed both constitutive and IL-6-inducible STAT3 activation through modulation of PIAS-3 and SOCS-3, thereby attenuating tumor growth and increasing sensitivity to paclitaxel. KEYWORDS: Brassinin | supplier | Dual IDO1/STAT3 inhibitor | CAS [105748-59-2] | L-Kynurenine | IDO1 | STAT3 | Inhibitor | IL-6 | PIAS-3 | SOCS-3 | antifungal | anticancer | natural | dithiocarbamate | paclitaxel
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產(chǎn)品品牌 axonmedchem
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Brassinin

Based on 88 publications in PubMed 10 10 88

Axon 2489

CAS [105748-59-2]

MF C11H12N2S2
MW 236.36

  • Purity: 98%
  • Soluble in DMSO

Brassinin

Description

Bioavailable dithiocarbamate with affinity for indoleamine 2,3-dioxygenase (IDO; Ki value 28 μM for human IDO) showing antifungal and anticancer activity. Moreover, Brassinin suppressed both constitutive and IL-6-inducible STAT3 activation through modulation of PIAS-3 and SOCS-3, thereby attenuating tumor growth and increasing sensitivity to paclitaxel.

KEYWORDS: Brassinin | supplier | Dual IDO1/STAT3 inhibitor | CAS [105748-59-2] | L-Kynurenine | IDO1 | STAT3 | Inhibitor | IL-6 | PIAS-3 | SOCS-3 | antifungal | anticancer | natural | dithiocarbamate | paclitaxel
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