| 產(chǎn)品名稱(chēng) | INCB 024360 - Epacadostat |
| 產(chǎn)品貨號(hào) | Axon 1733 CAS [1204669-58-8] MF C11H13BrFN7O4SMW 438.23 Purity: 98% Soluble in DMSO Description Potent competitive inhibitor of indoleamine 2,3-dioxygenase (IDO1, IC50 value 72 nM in vitro) with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; INCB024360 (Epacadostat) decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion. An analog of INCB 024360 (Axon 2215) is available as well. KEYWORDS:?INCB 24360 | ?IDO1 inhibitor | Axon 1733 | Epacadostat | INCB 024360 | INCB024360 | INCB24360 | CAS [1204669-58-8] | [1204669-37-3] | Kynurenine | cancer | immunotherapy | melanoma | hydroxamidine |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
INCB 024360 - EpacadostatAxon 1733 CAS [1204669-58-8] MF C11H13BrFN7O4S
DescriptionPotent competitive inhibitor of indoleamine 2,3-dioxygenase (IDO1, IC50 value 72 nM in vitro) with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; INCB024360 (Epacadostat) decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion. An analog of INCB 024360 (Axon 2215) is available as well. KEYWORDS:?INCB 24360 | ?IDO1 inhibitor | Axon 1733 | Epacadostat | INCB 024360 | INCB024360 | INCB24360 | CAS [1204669-58-8] | [1204669-37-3] | Kynurenine | cancer | immunotherapy | melanoma | hydroxamidine
Potent inhibitor of indoleamine 2,3-dioxygenase-1 (IDO1)
Chemical name(Z)-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-4-(2-(sulfamoylamino)ethylamino)-1,2,5-oxadiazole-3-carboximidamide Parent CAS No.[1204669-58-8] |
| 產(chǎn)品資料 |
