| 產(chǎn)品名稱 | BFF 122 - BF 5 |
| 產(chǎn)品貨號(hào) | Axon 2237 CAS [1152314-49-2] MF C17H19FN4O4MW 362.36 Purity: 99% Optical purity: Optically pure Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective inhibitor of kynurenine aminotransferase II (IC50 values ca. 1 μM and >30 μM for KAT II and KAT I respectively). Intrastriatal BFF 122 decreased newly formed KYNA by 66%, without influencing 3-HK or QUIN production in na?ve rats. References Certificates Categories Extra info L. Amori et al. On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo. J. Neurochem. 2009, 109, 316-325. ? F. Rossi et al. Crystal structure-based selective targeting of the pyridoxal 5'-phosphate dependent enzyme kynurenine aminotransferase II for cognitive enhancement. J. Med. Chem. 2010, 53, 5684-5689. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS KAT II EC 2.6.1.7 Potent and selective inhibitor of kynurenine aminotransferase II Chemical name (S)-10-(4-aminopiperazin-1-yl)-9-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Parent CAS No. [1152314-49-2] Order Size Unit Price Stock 5 mg €165.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
BFF 122 - BF 5Axon 2237 CAS [1152314-49-2] MF C17H19FN4O4
Description
Potent and selective inhibitor of kynurenine aminotransferase II (IC50 values ca. 1 μM and >30 μM for KAT II and KAT I respectively). Intrastriatal BFF 122 decreased newly formed KYNA by 66%, without influencing 3-HK or QUIN production in na?ve rats.
Potent and selective inhibitor of kynurenine aminotransferase II
Chemical name(S)-10-(4-aminopiperazin-1-yl)-9-fluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid Parent CAS No.[1152314-49-2] |
| 產(chǎn)品資料 |
