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AG 490 - Tyrphostin AG 490 | Tyrphostin B42

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Axon 1378 CAS [133550-30-8] MF C17H14N2O3MW 294.30 Purity: 99% Soluble in 0.1N NaOH(aq), DMSO, and Ethanol Description Janus Kinase 2 (JAK2) inhibitor References Certificates Categories Extra info N Miyamoto et al. The JAK2 inhibitor AG490 predominantly abrogates the growth of human B-precursor leukemic cells with 11q23 translocation or Philadelphia chromosome.?Leukemia?2001, 15, 1758-1768. ? O Sareila et al. JAK Inhibitors AG-490 and WHI-P154 Decrease IFN-γ-Induced iNOS Expression and NO Production in Macrophages.?Mediators Inflamm.?2006,2006(2),?16161. ? N?Meydan,?et al. Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor.Nature?1996,?379,?645-648. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology Epigenetics JAK-STAT EC 2.7.10.2 JAK JAK2 inhibitor Chemical name (E)-N-Benzyl-2-cyano-3-(3,4-dihydro xy-phenyl)-acrylamide Parent CAS No. [133550-30-8] Order Size Unit Price Stock 10 mg €65.00 In Stock

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axonmedchem

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