產(chǎn)品名稱 UK 432097
產(chǎn)品貨號 Axon 1193 CAS [380221-63-6] MF C40H47N11O6MW 777.87 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description Potent and selective A2A-adenosine receptor agonist; agent developed by Pfizer for chronic obstructive pulmonary disease (category Allergy/Respiratory); its high selectivity has made it useful for detailed mapping of the internal structure of the A2A receptor. Expert recommendation - a highly recommended tool in research of A2A receptor. References Certificates Categories Extra info C. Russo et al. Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma. Fundam. Clin. Pharmacol. 2006, 20, 9-19. ? Safety and efficacy of UK-432,097 in chronic obstructive pulmonary disease. ClinicalTrials.gov 2013. ? F. Xu et al. Structure of an Agonist-Bound Human A2A Adenosine Receptor. Science 2011, 332(6027), 322-327. (* UK 432097 used in this study was procured from Axon Medchem.)
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產(chǎn)品品牌 axonmedchem
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UK 432097

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 1193

CAS [380221-63-6]

MF C40H47N11O6
MW 777.87

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO

UK 432097

Description

Potent and selective A2A-adenosine receptor agonist; agent developed by Pfizer for chronic obstructive pulmonary disease (category Allergy/Respiratory); its high selectivity has made it useful for detailed mapping of the internal structure of the A2A receptor.

Expert recommendation - a highly recommended tool in research of A2A receptor.

Adenosine A2A agonist

Chemical name

6-[(2,2-Diphenylethyl)amino]-9-{(2R,3R,4S,5S)-5-[(ethylamino)carbonyl]-3,4-dihydroxytetrahydro-2-furanyl}-N-{2-[({[1-(2-pyridinyl)-4-piperidinyl]amino}carbonyl)amino]ethyl}-9H-purine-2-carboxamide

Parent CAS No.

[380221-63-6]
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