| 產(chǎn)品名稱 | VX 745 |
| 產(chǎn)品貨號 | Axon 1811 CAS [209410-46-8] MF C19H9Cl2F2N3OSMW 436.26 Purity: 99% Soluble in DMSO Description Highly potent and selective inhibitor of p38α MAP kinase (IC50: 10 nM); being 1000 fold selective over closely related kinases References Certificates Categories Extra info JP Duffy et al. The discovery of VX-745: a novel and selective p38α kinase inhibitor. ACS Med. Chem. Lett. 2011, 2, 758.? ? MC Bagley et al. Rapid synthesis of VX-745: p38 MAP kinase inhibition in Werner syndrome cells. Bioorg. Med. Chem. Lett. 2007, 17(8), 5107-5110. ? JJ Haddad. VX-745. Vertex Pharmaceuticals. Curr. Opin. Investig. Drugs. 2001, 2(8), 1070-1076.? Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK (p38) MAPK EC 2.7.11.24 Inhibitor of p38α MAP kinase Chemical name 5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one Parent CAS No. [209410-46-8] Order Size Unit Price Stock 5 mg €90.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
VX 745Axon 1811 CAS [209410-46-8] MF C19H9Cl2F2N3OS
Description
Highly potent and selective inhibitor of p38α MAP kinase (IC50: 10 nM); being 1000 fold selective over closely related kinases
Inhibitor of p38α MAP kinase
Chemical name5-(2,6-dichlorophenyl)-2-(2,4-difluorophenylthio)-6H-pyrimido[1,6-b]pyridazin-6-one Parent CAS No.[209410-46-8] |
| 產(chǎn)品資料 |
