| 產(chǎn)品名稱 | MC70 hydrochloride |
| 產(chǎn)品貨號 | Axon 2591 CAS [N.A.] MF C24H25NO3.HClMW 411.92 Purity: 98% Soluble in DMSO Description Potent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively), with potential as novel anticancer agent with both cytostatic and cytotoxic characteristics. MC70, as an inhibitor of the ABC transporter ABCB1 (aka MDR1), potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. *Sold in collaboration with Biofordrug srl |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
MC70 hydrochlorideAxon 2591 CAS [N.A.] MF C24H25NO3.HCl
DescriptionPotent P-gp inhibitor with good selectivity towards BCRP pump (EC50 values 0.05 μM, 0.69 μM, 9.3 μM, and 73 μM for Caco-2, MDR1, MRP1, and BCRP inhibition, respectively), with potential as novel anticancer agent with both cytostatic and cytotoxic characteristics. MC70, as an inhibitor of the ABC transporter ABCB1 (aka MDR1), potentiates Doxorubicin efficacy in colon and breast cancer in vitro treatment. *Sold in collaboration with Biofordrug srl KEYWORDS: MC 70 hydrochloride | supplier | PGP inhibitor | MC70 HCl | CAS [1031367-64-2] | P-glycoprotein | P-GP | Inhibitor | ABC transporter | ABCB1 | MDR1 | BCRP | Caco-2 | breast cancer
Potent P-gp inhibitor with good selectivity towards BCRP pump
Chemical name4'-((6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)methyl)biphenyl-4-ol hydrochloride Parent CAS No.[1031367-64-2] |
| 產(chǎn)品資料 |
