產(chǎn)品名稱 XMD 8-92 trifluoroacetate
產(chǎn)品貨號(hào) Axon 1621 CAS [1234480-50-2] MF C26H30N6O3.C2HF3O2MW 588.58 Purity: 99% Soluble in water and DMSO Description Potent and selective inhibitor of big MAP kinase 1 (BMK1/ERK5). Note: Free base form of XMD 8-92 (Axon 1846) is also available References Certificates Categories Extra info Q. Yang et al. Pharmacological Inhibition of BMK1 Suppresses Tumor Growth through Promyelocytic Leukemia Protein. Cancer Cell, 2010, 18(3), 258-267. ? Q Yang and JD Lee. Targeting the BMK1 MAP Kinase Pathway in Cancer Therapy.?Clin. Cancer Res. 2011, 17, 3527-3532. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK EC 2.7.11.24 ERK BMK1 inhibitor; ERK5 inhibitor Chemical name 2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 2,2,2-trifluoroacetate Source information Sold under agreement with the Dana-Faber Cancer Institute Parent CAS No. [1234480-50-2] Order Size Unit Price Stock 2 mg €70.00 In Stock
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XMD 8-92 trifluoroacetate

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 1621

CAS [1234480-50-2]

MF C26H30N6O3.C2HF3O2
MW 588.58

  • Purity: 99%
  • Soluble in water and DMSO

XMD 8-92 trifluoroacetate

Description

Potent and selective inhibitor of big MAP kinase 1 (BMK1/ERK5).

Note: Free base form of XMD 8-92 (Axon 1846) is also available

BMK1 inhibitor; ERK5 inhibitor

Chemical name

2-(2-ethoxy-4-(4-hydroxypiperidin-1-yl)phenylamino)-5,11-dimethyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one 2,2,2-trifluoroacetate

Source information

Sold under agreement with the Dana-Faber Cancer Institute

Parent CAS No.

[1234480-50-2]
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