| 產(chǎn)品名稱 | BAM 7 |
| 產(chǎn)品貨號(hào) | Axon 2185 CAS [331244-89-4] MF C21H19N5O2SMW 405.47 Purity: 98% Soluble in DMSO Description Selective small-molecule activator of proapoptotic BAX (IC50 value 3.3 μM) that binds to the BH3 binding domain without interacting with other BH3-binding pockets of antiapoptotic proteins or proapoptotic BAK. BAM 7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. References Certificates Categories Extra info E. Gavathiotis et al. Direct and selective small-molecule activation of proapoptotic BAX. Nat. Chem. Biol. 2012, 8, 639-645. Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology p53-Tumor Suppression Bcl Selective small-molecule activator of proapoptotic BAX Chemical name 4-(2-(2-ethoxyphenyl)hydrazono)-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one Parent CAS No. [331244-89-4] Order Size Unit Price Stock 10 mg €105.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
BAM 7Axon 2185 CAS [331244-89-4] MF C21H19N5O2S
Description
Selective small-molecule activator of proapoptotic BAX (IC50 value 3.3 μM) that binds to the BH3 binding domain without interacting with other BH3-binding pockets of antiapoptotic proteins or proapoptotic BAK. BAM 7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death.
Selective small-molecule activator of proapoptotic BAX
Chemical name4-(2-(2-ethoxyphenyl)hydrazono)-3-methyl-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5(4H)-one Parent CAS No.[331244-89-4] |
| 產(chǎn)品資料 |
