產(chǎn)品名稱 S3QEL 2
產(chǎn)品貨號 Axon 2544 CAS [890888-12-7] MF C19H25N5MW 323.44 Purity: 99% Soluble in DMSO Description Suppressor of superoxide production from mitochondrial complex III (IC50 value 1.7 μM against superoxide production mediated by the outer Q-binding site of complex III (site IIIQo)). S3QEL-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells, and strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets. S3QEL-2 modulates HIF-1α activation without directly affecting metabolism. KEYWORDS: S3QEL 2 | supplier | Complex III modulator | S3QEL2 | CAS [890888-12-7] | Quinol | Complex III | Coenzyme Q | superoxide | ROS | mitochondria | Q-binding site | site III Qo | oxidative stress | reactive oxygen species
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產(chǎn)品品牌 axonmedchem
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S3QEL 2

Based on 2 reference(s) in Google Scholar 9 10 2

Axon 2544

CAS [890888-12-7]

MF C19H25N5
MW 323.44

  • Purity: 99%
  • Soluble in DMSO

S3QEL 2

Description

Suppressor of superoxide production from mitochondrial complex III (IC50 value 1.7 μM against superoxide production mediated by the outer Q-binding site of complex III (site IIIQo)). S3QEL-2 protects against ROS-induced, JNK-mediated cell stress in pancreatic β-cells, and strongly mitigates the oxidative stress-induced apoptosis that limits the yield of functional β-cells from intact islets. S3QEL-2 modulates HIF-1α activation without directly affecting metabolism.

KEYWORDS: S3QEL 2 | supplier | Complex III modulator | S3QEL2 | CAS [890888-12-7] | Quinol | Complex III | Coenzyme Q | superoxide | ROS | mitochondria | Q-binding site | site III Qo | oxidative stress | reactive oxygen species
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