產(chǎn)品名稱

BIX 01294 trihydrochloride

產(chǎn)品貨號(hào)

Axon 1692 CAS [935693-62-2] MF C28H38N6O2.3HClMW 600.02 Purity: 99% Soluble in water and DMSO Description G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor; Recently, BIX-01294 and RG108 (Axon 1691) have been reported to enhance the efficiency of iPS cell generation *Promotion

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產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

BIX 01294 trihydrochloride

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1692

CAS [935693-62-2]

MF C28H38N6O2.3HCl
MW 600.02

Purity: 99%
Soluble in water and DMSO

BIX 01294 trihydrochloride

Description

G9a-like protein and G9a histone lysine methyltransferase (HMTase) inhibitor; Recently, BIX-01294 and RG108 (Axon 1691) have been reported to enhance the efficiency of iPS cell generation

*Promotion: BIX 01294 HCl is also part of Inhibitor Set(s):

Axon 5008

Y Chang et al. Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294. Nat. Struct. Mol. Biol. 2009, 16 312.

S Kubicek et al. Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. Mol. Cell. 2007, 25,?473.?

Y Shi et al. Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds. Cell Stem Cell 2008, 3, 568-574.

Y Shi et al. A combined chemical and genetic approach for the generation of induced pluripotent stem cells. Cell Stem Cell. 2008, 2(6), 525-528.

Certificate of Analysis
Material Safety Data Sheet

Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Epigenetics Stem Cell EC 2.1.1.43 HMTase

HMTase inhibitor (G9a and G9a-like protein)

Chemical name

N-(1-benzylpiperidin-4-yl)-6,7-dimethoxy-2-(4-methyl-1,4-diazepan-1-yl)quinazolin-4-amine trihydrochloride

Parent CAS No.

[935693-62-2]

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