產(chǎn)品名稱 AMI-1 - AMI-1 sodium salt
產(chǎn)品貨號(hào) Axon 2863 CAS [20324-87-2] MF C21H14N2Na2O9S2MW 548.45 Purity: 99% Soluble in water and DMSO Description AMI-1 specifically inhibits protein arginine N-methyltransferase (PRMT) activity in vitro (IC50 values of 8.81 and 3.04 μM for PRMT1 and Hmt1p, respectively). Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. HIV-1 integrase inhibitor (IC50 value of 4 μM). KEYWORDS: AMI-1 | supplier | PRMT inhibitor | AMI-1 sodium salt | AMI 1 | AMI1 | CAS [20324-87-2] | [134-47-4] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes | HIV-1 | Integrase | Protein Arginine N-Methyltransferase
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AMI-1 - AMI-1 sodium salt

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 2863

CAS [20324-87-2]

MF C21H14N2Na2O9S2
MW 548.45

  • Purity: 99%
  • Soluble in water and DMSO

AMI-1

Description

AMI-1 specifically inhibits protein arginine N-methyltransferase (PRMT) activity in vitro (IC50 values of 8.81 and 3.04 μM for PRMT1 and Hmt1p, respectively). Furthermore, AMI-1 prevents in vivo arginine methylation of cellular proteins and can modulate nuclear receptor-regulated transcription from estrogen and androgen response elements, thus operating as a brake on certain hormone actions. HIV-1 integrase inhibitor (IC50 value of 4 μM).

KEYWORDS: AMI-1 | supplier | PRMT inhibitor | AMI-1 sodium salt | AMI 1 | AMI1 | CAS [20324-87-2] | [134-47-4] | Non Selective (Arginine Sites Proteins) | PRMT | Inhibitor | Enzymes | HIV-1 | Integrase | Protein Arginine N-Methyltransferase

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