產(chǎn)品名稱 ABT 239 tartrate
產(chǎn)品貨號(hào) Axon 1510 CAS [ 460748-71-4] MF C22H22N2O.C4H6O6MW 480.51 Purity: 98% Optical purity: >98% ee Soluble in water and DMSO Description Potent and selective histamine H3 receptor antagonist or inverse agonist; a highly recommended tool for animal research into H3 antagonist / inverse agonist References Certificates Categories Extra info TA Esbenshade et al. Pharmacological properties of ABT-239 [4-(2-{2-[(2R)-2-Methylpyrrolidinyl]ethyl}-benzofuran-5-yl)benzonitrile]: I. Potent and selective histamine H3 receptor antagonist with drug-like properties. J. Ph. Exp. Ther. 2005, 313, 165. ? GB Fox et al. Pharmacological properties of ABT-239 : II. Neurophysiological characterization and broad preclinical efficacy in cognition and schizophrenia of a potent and selective histamine H3 receptor antagonist. J. Ph. Exp. Ther. 2005, 313,? 176–90.? ? M Cowart et al. 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and related 2-aminoethylbenzofuran H3 receptor antagonists potently enhance cognition and attention. J. Med. Chem. 2005, 48 (1), 38–55. Certificate of Analysis Material Safety Data Sheet CNS Diabetes & Metabolism Immunology Pain & Inflammation H3 A18 H3 antagonist/inverse agonist Chemical name 4-{2-[2-((R)-2-Methyl-pyrrolidin-1-yl)-ethyl]-benzofuran-5-yl}-benzonitrile tartrate Parent CAS No. [460746-46-7] Order Size Unit Price Stock 5 mg €135.00 In Stock
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