產(chǎn)品名稱 PF 4708671 - PF 04708671
產(chǎn)品貨號 Axon 1602 CAS [1255517-76-0] MF C19H21F3N6MW 390.41 Purity: 99% Soluble in DMSO Description Highly specific and cell-permeable p70 ribosomal S6 kinase (S6K1) inhibitor with Ki of 20 nM and IC50 of 160 nM; having no effect on the closely related RSK and MSK kinases; Useful tool for delineating S6K1-specific roles downstream of mTOR References Certificates Categories Extra info LR Pearce et al. Characterisation of PF-4708671 a novel and highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). Biochem. J. 2010, 431, 245-255. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology MAPK PI3K-Akt-mTOR EC 2.7.11.1 p70-RSK Pfizer Licensed Products RSK inhibitor (p70 RSK specific) Chemical name 2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole Source information Pfizer compound; Sold for research purposes under agreement from Pfizer Inc. Parent CAS No. [1255517-76-0] Order Size Unit Price Stock 10 mg €110.00 In Stock
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PF 4708671 - PF 04708671

Based on 15 reference(s) in Google Scholar 8 10 15

Axon 1602

CAS [1255517-76-0]

MF C19H21F3N6
MW 390.41

  • Purity: 99%
  • Soluble in DMSO

PF 4708671

Description

Highly specific and cell-permeable p70 ribosomal S6 kinase (S6K1) inhibitor with Ki of 20 nM and IC50 of 160 nM; having no effect on the closely related RSK and MSK kinases; Useful tool for delineating S6K1-specific roles downstream of mTOR
RSK inhibitor (p70 RSK specific)

Chemical name

2-((4-(5-ethylpyrimidin-4-yl)piperazin-1-yl)methyl)-5-(trifluoromethyl)-1H-benzo[d]imidazole

Source information

Pfizer compound; Sold for research purposes under agreement from Pfizer Inc.

Parent CAS No.

[1255517-76-0]
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