| 產(chǎn)品名稱(chēng) | RO 3306 |
| 產(chǎn)品貨號(hào) | Axon 1530 CAS [872573-93-8] MF C18H13N3OS2MW 351.45 Purity: 99% Soluble in DMSO Description Selective CDK 1 inhibitor (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively), which induces cell cycle arrest and actively enhances downstream p53 signaling to promote apoptosis in AML cell lines References Certificates Categories Extra info LT Vassilev et al. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc Natl Acad Sci USA. 2006, 103(28), 10660–10665. ? K Kojima et al. The CDK1 inhibitor RO-3306 enhances p53-mediated Bax activation and mitochondrial apoptosis in AML. Cancer Sci. 2009, 100(6), 1128–1136.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology p53-Tumor Suppression EC 2.7.11.22 CDK CDK1 inhibitor Chemical name 2-[[Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one Parent CAS No. [872573-93-8] Order Size Unit Price Stock 5 mg €90.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話(huà)：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
RO 3306Axon 1530 CAS [872573-93-8] MF C18H13N3OS2
Description
Selective CDK 1 inhibitor (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively), which induces cell cycle arrest and actively enhances downstream p53 signaling to promote apoptosis in AML cell lines
CDK1 inhibitor
Chemical name2-[[Thiophen-2-yl)methyl]amino]-5-[1-(quinolin-6-yl)meth-(Z)-ylidene]thiazol-4-one Parent CAS No.[872573-93-8] |
| 產(chǎn)品資料 |
