產品名稱 NSC 319726
產品貨號 Axon 2016 CAS [71555-25-4] MF C11H14N4SMW 234.32 Purity: 99% Soluble in DMSO Description Reactivator of the p53 mutant p53R175; NSC319726 selectively kills cancer cells with a p53R175 mutations; it restores the transcriptional functions of p53R175 References Certificates Categories Extra info X Yu et al. Allele-Specific p53 Mutant Reactivation. Cancer Cell.?2012, 21(5), 614–625.?? ? C Harrison. Anticancer drugs: Reactivating p53. Nature Reviews Drug Discovery 2012, 11, 517.? ? Mutant p53 Alleles Can Be Restored to the Wild-Type Conformation. Cancer Discovery 2012, 2(7), 581. ? VV Prabhu et al. Therapeutic targeting of the p53 pathway in cancer stem cells. 2012, 16(12), 1161-1174.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology p53 Transcription Factors DNA-damage Response Ubiquitin TF class 4.3.1 Reactivator of the p53 mutant p53R175 Chemical name N'-(1-(pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide Parent CAS No. [71555-25-4] Order Size Unit Price Stock 5 mg €95.00 In Stock
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NSC 319726

Based on 8 reference(s) in Google Scholar 9 10 8

Axon 2016

CAS [71555-25-4]

MF C11H14N4S
MW 234.32

  • Purity: 99%
  • Soluble in DMSO

NSC 319726

Description

Reactivator of the p53 mutant p53R175; NSC319726 selectively kills cancer cells with a p53R175 mutations; it restores the transcriptional functions of p53R175
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