| 產(chǎn)品名稱 | RITA - NSC 652287 |
| 產(chǎn)品貨號 | Axon 2009 CAS [213261-59-7] MF C14H12O3S2MW 292.37 Purity: 98% Soluble in DMSO Description Small molecule p53 activator; MDM2 inhibitor References Certificates Categories Extra info MN Saha et al. RITA Inhibits Multiple Myeloma Cell Growth through Induction of p53-Mediated Caspase-Dependent Apoptosis and Synergistically Enhances Nutlin-Induced Cytotoxic Responses. Mol. Cancer Ther. 2010, 9, 3041.? ? N Issaeva et al. Small molecule RITA binds to p53, blocks p53?HDM-2 interaction and activates p53 function in tumors. Nature Med.?2004, 10, 1321-1328.? ? MN Saha et al. Targeting p53 via JNK pathway: a novel role of RITA for apoptotic signaling in multiple myeloma. PLoS One. 2012, 7(1), e30215.? Certificate of Analysis Material Safety Data Sheet Apoptosis Cell Cycle Regulation Cell Signaling & Oncology Transcription Factors p53-Tumor Suppression DNA-damage Response Ubiquitin EC 6.3.2.19 HDM-MDM Activates p53 through inhibition of MDM2 Chemical name (5,5'-(furan-2,5-diyl)bis(thiophene-5,2-diyl))dimethanol Parent CAS No. [213261-59-7] Order Size Unit Price Stock 10 mg €105.00 In Stock |
| 產(chǎn)品價格 | 現(xiàn)貨詢價，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
RITA - NSC 652287Axon 2009 CAS [213261-59-7] MF C14H12O3S2
Description
Small molecule p53 activator; MDM2 inhibitor
Activates p53 through inhibition of MDM2
Chemical name(5,5'-(furan-2,5-diyl)bis(thiophene-5,2-diyl))dimethanol Parent CAS No.[213261-59-7] |
| 產(chǎn)品資料 |
