| 產(chǎn)品名稱(chēng) | D 106669 |
| 產(chǎn)品貨號(hào) | Axon 1719 CAS [938444-93-0] MF C17H18N6OMW 322.36 Purity: 98% Soluble in DMSO Description Highly potent and selective PI3K inhibitor, selectively inhibiting class I PI3K (PI3Kα IC50 <10 nM, >3 log selectivity against tyrosine or serine/threonine kinases, except ERK1 and 2) and showed some activity in A549 (lung cancer) xenografts mouse model at oral dose of 30 mg/kg twice daily References Certificates Categories Extra info SM Maira et al. Discovery of novel anticancer therapeutics targeting the PI3K/Akt/mTOR pathway. Future Med. Chem. 2009, 1(1), 137-155. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology PI3K PI3K-Akt-mTOR EC 2.7.1.153 Potent and selective PI3K inhibitor Chemical name 1-ethyl-3-(3-(p-tolylamino)pyrido[2,3-b]pyrazin-6-yl)urea Parent CAS No. [938444-93-0] Order Size Unit Price Stock 2 mg €85.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢(xún)價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
D 106669Axon 1719 CAS [938444-93-0] MF C17H18N6O
Description
Highly potent and selective PI3K inhibitor, selectively inhibiting class I PI3K (PI3Kα IC50 <10 nM, >3 log selectivity against tyrosine or serine/threonine kinases, except ERK1 and 2) and showed some activity in A549 (lung cancer) xenografts mouse model at oral dose of 30 mg/kg twice daily
Potent and selective PI3K inhibitor
Chemical name1-ethyl-3-(3-(p-tolylamino)pyrido[2,3-b]pyrazin-6-yl)urea Parent CAS No.[938444-93-0] |
| 產(chǎn)品資料 |
