產(chǎn)品名稱(chēng)

MDL 100907 - Volinanserin | MDL 100907, (R)-(+)-

產(chǎn)品貨號(hào)

Axon 1104 CAS [139290-65-6] MF C22H28FNO3MW 373.46 Purity: 99% Optical purity: 98% ee Soluble in DMSO and Ethanol Description A highly selective 5-HT2A antagonist, more active enantiomer of MDL 100151 (Axon 1103) in comparison with S-(-)-enantiomer (Axon 1105); a highly recommended tool compound in researching into 5-HT2A receptors References Certificates Categories Extra info SM Sorensen et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. JPET 1993, 266(2), 684-691.?? ? J H Kehne et al.?Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol.?1996, 15, 116-124.? ? T de Paulis. M-100907 (Aventis). Curr Opin Investig Drugs. 2001, 2(1), 123-32. ? GB Vary et al. M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats. Neuropsychopharmacol. 1999, 20(4), 311-21.? ? RY Wang and X Liang. M100907 and Clozapine, but not Haloperidol or Raclopride, Prevent Phencyclidine-Induced Blockade of NMDA Responses in Pyramidal Neurons of the Rat Medial Prefrontal Cortical Slice. Neuropsychopharmacol. 1998, 19, 74-85.? Certificate of Analysis Material Safety Data Sheet CNS 5-HT2A A17 5-HT2A antagonist Chemical name (R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol Parent CAS No. [139290-65-6] Order Size Unit Price Stock 5 mg €110.00 In Stock

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產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

MDL 100907 - Volinanserin | MDL 100907, (R)-(+)-

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1104

CAS [139290-65-6]

MF C22H28FNO3
MW 373.46

Purity: 99%
Optical purity: 98% ee
Soluble in DMSO and Ethanol

MDL 100907

Description

A highly selective 5-HT2A antagonist, more active enantiomer of MDL 100151 (Axon 1103) in comparison with S-(-)-enantiomer (Axon 1105); a highly recommended tool compound in researching into 5-HT2A receptors

SM Sorensen et al. Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies. JPET 1993, 266(2), 684-691.??

J H Kehne et al.?Effects of the Selective 5-HT2A Receptor Antagonist MDL 100,907 on MDMA-Induced Locomotor Stimulation in Rats.Neuropsychopharmacol.?1996, 15, 116-124.?

T de Paulis. M-100907 (Aventis). Curr Opin Investig Drugs. 2001, 2(1), 123-32.

GB Vary et al. M100907, a serotonin 5-HT2A receptor antagonist and putative antipsychotic, blocks dizocilpine-induced prepulse inhibition deficits in Sprague-Dawley and Wistar rats. Neuropsychopharmacol. 1999, 20(4), 311-21.?

RY Wang and X Liang. M100907 and Clozapine, but not Haloperidol or Raclopride, Prevent Phencyclidine-Induced Blockade of NMDA Responses in Pyramidal Neurons of the Rat Medial Prefrontal Cortical Slice. Neuropsychopharmacol. 1998, 19, 74-85.?

Certificate of Analysis
Material Safety Data Sheet

CNS 5-HT2A A17

5-HT2A antagonist

Chemical name

(R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol

Parent CAS No.

[139290-65-6]

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