| 產(chǎn)品名稱 | LY 2886721 hydrochloride |
| 產(chǎn)品貨號(hào) | Axon 1964 CAS [1262036-49-6] MF C18H16F2N4O2S.HClMW 426.87 Purity: 99% Optical purity: Optically pure Soluble in DMSO Description Orally active cell-permeable inhibitor of human β-secretase (BACE-1); potential agent to treat Alzheimer's Disease References Certificates Categories Extra info M Townsend. When will Alzheimer's disease be cured? A pharmaceutical perspective. J. Alzheimers Dis. 2011, 24 (Suppl 2), 43-52.? ? P May et al. Preclinical characterization of LY2886721: A BACE1 inhibitor in clinical development for early Alzheimer's disease. Alzheimer's & Dementia 2012, 8(4), 95.??? ? B Willis et al. Central BACE1 inhibition by LY2886721 produces opposing effects on APP processing as reflected by cerebrospinal fluid sAPPalpha and sAPPbeta. Alzheimer's & Dementia 2012, 8(4), 582. ? F Martenyi et al. BACE inhibitor LY2886721 safety and central and peripheral PK and PD in healthy subjects (HSs). Alzheimer's & Dementia 2012, 8(4), 583. Certificate of Analysis Material Safety Data Sheet Cell Signaling & Oncology CNS BACE-1 EC 3.4.23.46 BACE 1 inhibitor Chemical name N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride Parent CAS No. [1262036-50-9] Order Size Unit Price Stock 5 mg €105.00 In Stock |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
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| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
LY 2886721 hydrochlorideAxon 1964 CAS [1262036-49-6] MF C18H16F2N4O2S.HCl
Description
Orally active cell-permeable inhibitor of human β-secretase (BACE-1); potential agent to treat Alzheimer's Disease
BACE 1 inhibitor
Chemical nameN-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide hydrochloride Parent CAS No.[1262036-50-9] |
| 產(chǎn)品資料 |
