產(chǎn)品名稱

SU 5402

產(chǎn)品貨號(hào)

Axon 1667 CAS [215543-92-3] MF C17H16N2O3MW 296.32 Purity: 99% Soluble in 0.1N NaOH(aq) and DMSO Description Fibroblast growth factor receptor (FGFR) inhibitor. A convenient set of FGFR inhibitor SU 5402 (Axon 1667), MEK inhibitor PD 184352 (Axon 1368) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (conventional 3i, Axon 2129), was used together to sustain mouse embryonic stem cell (mESC) self-renewal. *Promotion

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現(xiàn)貨詢價(jià)，電話：010-67529703

產(chǎn)品規(guī)格

產(chǎn)品品牌

axonmedchem

產(chǎn)品概述

產(chǎn)品詳情

SU 5402

Based on 16 reference(s) in Google Scholar 9 10 16

Axon 1667

CAS [215543-92-3]

MF C17H16N2O3
MW 296.32

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

SU 5402

Description

Fibroblast growth factor receptor (FGFR) inhibitor.

A convenient set of FGFR inhibitor SU 5402 (Axon 1667), MEK inhibitor PD 184352 (Axon 1368) and GSK-3 inhibitor CHIR 99021 (Axon 1386) (conventional 3i, Axon 2129), was used together to sustain mouse embryonic stem cell (mESC) self-renewal.

*Promotion: SU 5402 is also part of Inhibitor Set(s):

Axon 2129

Axon 5006

Axon 5007

EK Grand et al. Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Leukemia 2004, 18, 962–966.

Y Tanaka et al. FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination. Nature 2005, 435(7039), 172-177.

JL Paterson et al. Preclinical studies of fibroblast growth factor receptor 3 as a therapeutic target in multiple myeloma. Br. J. Haematol. 2004, 124(5), 595-603.

Certificate of Analysis
Material Safety Data Sheet

Angiogenesis Cell Signaling & Oncology Stem Cell VEGFR RTK class IV and V; EC 2.7.10.1 FGFR

Fibroblast growth factor receptor (FGFR) inhibitor

Chemical name

3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid

Parent CAS No.

[215543-92-3]

產(chǎn)品資料