| 產(chǎn)品名稱 | AZD 9291 - Osimertinib |
| 產(chǎn)品貨號(hào) | Axon 2342 CAS [1421373-65-0] MF C28H33N7O2MW 499.61 Purity: 99% Soluble in 0.1N HCl(aq) and DMSO Description A potent oral, third-generation EGFR TKI, that irreversibly and selectively targets both sensitizing and resistant T790M+ mutant EGFR while harboring less activity toward wild-type EGFR (IC50 values 1 nM,12 nM, 5 nM, and 184 nM against L858R/T790M-, L858R-, L861Q-mutant, and WT EGFR, respectively). KEYWORDS:?AZD 9291 | supplier | EGFR inhibitor | Osimertinib |?AZD9291 | CAS [1421373-65-0] | EGF | EGFR | Non-small cell lung cancer | NSCLC | ERBB | HER | T790M | TKI | cancer | oncology |
| 產(chǎn)品價(jià)格 | 現(xiàn)貨詢價(jià)，電話：010-67529703 |
| 產(chǎn)品規(guī)格 | |
| 產(chǎn)品品牌 | axonmedchem |
| 產(chǎn)品概述 | |
| 產(chǎn)品詳情 |
AZD 9291 - OsimertinibAxon 2342 CAS [1421373-65-0] MF C28H33N7O2
DescriptionA potent oral, third-generation EGFR TKI, that irreversibly and selectively targets both sensitizing and resistant T790M+ mutant EGFR while harboring less activity toward wild-type EGFR (IC50 values 1 nM,12 nM, 5 nM, and 184 nM against L858R/T790M-, L858R-, L861Q-mutant, and WT EGFR, respectively). KEYWORDS:?AZD 9291 | supplier | EGFR inhibitor | Osimertinib |?AZD9291 | CAS [1421373-65-0] | EGF | EGFR | Non-small cell lung cancer | NSCLC | ERBB | HER | T790M | TKI | cancer | oncology
Potent oral, irreversible, third-generation EGFR TKI with selectivity for mutant EGFRs
Chemical nameN-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-(4-(1-methyl-1H-indol-3-yl)pyrimidin-2-ylamino)phenyl)acrylamide Parent CAS No.[1421373-65-0] |
| 產(chǎn)品資料 |
